Lifelong exposure to air pollution and greenness in relation to asthma, rhinitis and lung function in adulthood

To investigate if air pollution and greenness exposure from birth till adulthood affects adult asthma, rhinitis lung function. Methods: We analysed data 3428 participants (mean age 28) in the RHINESSA study Norway Sweden. Individual mean annual residential exposures to nitrogen dioxide (NO2), particulate matter (PM10 PM2.5), black carbon (BC), ozone (O3) (normalized difference vegetation index (NDVI)) were averaged across susceptibility windows (0–10 years, 10–18 lifetime, (year before participation)) relation physician diagnosed asthma (ever/allergic/non-allergic), attack last 12 months, current low function (lower limit of normal (LLN), z-scores forced expiratory volume one second (FEV1), vital capacity (FVC) FEV1/FVC below 1.64). performed logistic regression for attack, LLN (clustered with family centre), conditional a matched case-control design ever/allergic/non-allergic asthma. Multivariable models adjusted parental education. Results: Childhood, adolescence NO2, PM10 O3 associated an increased risk attacks (ORs between 1.29 2.25), but not For rhinitis, seemed be most important. Childhood PM2.5 lower function, particular FEV1 (range ORs 2.65 4.21). No associations NDVI or revealed, was FVC all 1.39 1.74). Conclusions: Air childhood, attacks, adulthood. Greenness factor